梁鑫淼-全讯国际

梁鑫淼 
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电话: 021-64250627
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传真: 021-64250627
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e-mail:
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  个人简介
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        1987年从杭州大学免试进入大连化物所，攻读色谱专业硕士学位，师从卢佩章院士、张玉奎院士。两年后，又以优异成绩直接攻读博士学位，1992年12月毕业获博士学位并留所工作。历任大连化物所助理研究员、副研究员、研究员，大连化物所副所长；现任华东理工大学特聘教授，制药工程与过程化学研究中心主任，厦门大学“材料与生命过程分析科学”国家教委开放实验室学术委员会委员、中国仪器仪表学会分析仪器学会理事。
      自1995年以来一直从事中药的化学物质基础研究，承担并完成了国家973项目“方剂关键科学问题的基础研究”中“方剂化学物质基础的研究”课题、中国科学院知识创新工程领域前沿项目“中药黄芪对白血病的基因调控研究及治疗药物的开发”。参加并完成国家自然科学基金重点项目“中药药效组分的指纹图谱分析的方法研究”；作为首席科学家承担“中国科学院知识创新工程”重大项目“基于现代理论和技术的复方中药系统研究”。近年来，在国内外专业杂志上已发表研究报告239篇，其中angew chem int ed, j am chem soc, anal chem, chem commun, j org chem, environ sci technol, j chromatogr等sci论文118篇，已培养博士33名、博士后5名、硕士9名，指导博士生27名、博士后3名、硕士生7名。
   
   

研究方向
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        学科涉及制药工程、药物化学、有机化学和分析化学等，主要研究方向为：

1.中药系统分离纯化与化学表征技术研究。
  2.新型分离材料和分离技术研究与开发。
  3.有机合成方法学及其在药物合成中的应用。
  4.制药过程化学的研究与开发。

获奖成果
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    2001.12 辽宁省自然科学一等奖
  1993.10 第七届中国图书奖
  2000.4 全国先进工作者称号
  1999.10 辽宁省科技功勋奖
  1998.5 辽宁青年五四奖章
  1997.4 全国五一劳动奖章
  1997.3 首届“中国科学院杰出青年”称号
  1997.2 “艰苦奋斗的创业者”称号
  1997.3 中华人民共和国国务院政府特殊津贴
  1995.9 中国科学院青年科学家奖二等奖

代表性论著
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    代表性论著：(2005年以后)：
  1. zhang, z. p.; zheng, y. j.; chen, j. p.; zhang, q.; ni, y. w.; liang, x. m., facile synthesis of monodisperse magnesium oxide microspheres via seed-induced precipitation and their applications in high-performance liquid chromatography. advanced functional materials 2007, in press.

2. guo, z. m.; lei, a. w.; zhang, y. p.; xu, q.; xue, x. y.; zhang, f. f.; liang, x. m., “click saccharides”: novel separation materials for hydrophilic interaction liquid chromatography. chemical communications 2007, in press.

3. zhang, z. p.; zheng, y. j.; zhang, j. x.; zhang, q.; chen, j. p.; liu, z. m.; liang, x. m., synthesis and shape evolution of monodisperse basic magnesium carbonate microspheres. crystal growth & design 2007, 7, (2), 337-342.

4. zhou, d. y.; xu, q.; xue, x. y.; zhang, f. f.; liang, x. m., identification of o-diglycosyl flavanones in fructus aurantii by liquid chromatography with electrospray ionization and collision-induced dissociation mass spectrometry. journal of pharmaceutical and biomedical analysis 2006, 42, (4), 441-448.

5. zhao, h. x.; xue, x. y.; xu, q.; zhang, f. f.; liang, x. m., gas chromatographic peak identification for polybrominated diphenyl ethers under different temperature programs. journal of chromatography a 2006, 1107, (1-2), 248-256.

6. zhang, z. p.; zheng, y. j.; ni, y. w.; liu, z. m.; chen, j. p.; liang, x. m., temperature- and ph-dependent morphology and ft-ir analysis of magnesium carbonate hydrates. journal of physical chemistry b 2006, 110, (26), 12969-12973.

7. zhang, z. p.; zhang, s. g.; chen, j. p.; liu, z. m.; liang, x. m., characterization of the surface properties of mg/al oxides by the solvation parameter model. journal of chromatography a 2006, 1115, (1-2), 58-63.

8. zhang, x. l.; martens, d.; kramer, p. m.; kettrup, a. a.; liang, x. m., development and application of a sol-gel immunosorbent-based method for the determination of isoproturon in surface water. journal of chromatography a 2006, 1102, (1-2), 84-90.

9. zhang, x. l.; martens, d.; kramer, p. m.; kettrup, a. a.; liang, x. m., on-line immunoaffinity column-liquid chromatography-tandem mass spectrometry method for trace analysis of diuron in wastewater treatment plant effluent sample. journal of chromatography a 2006, 1133, (1-2), 112-118.

10. zhang, g. f.; liu, r. h.; xu, q.; ma, l. x.; liang, x. m., sodium nitrite-catalyzed oxybromination of aromatic compounds and aryl ketones with a combination of hydrobromic acid and molecular oxygen under mild conditions. advanced synthesis & catalysis 2006, 348, (7-8), 862-866.

11. zeng, q. h.; hu, x. p.; duan, z. c.; liang, x. m.; zheng, z., unsymmetrical ferrocenylethylamine-derived monophosphoramidites: highly efficient chiral ligands for rh-catalyzed enantioselective hydrogenation of enamides and alpha-dehydroamino acid derivatives. journal of organic chemistry 2006, 71, (1), 393-396.

12. zeng, g. f.; xiao, h. b.; liu, j. x.; liang, x. m., identification of phenolic constituents in radix salvia miltiorrhizae by liquid chromatography/electrospray ionization mass spectrometry. rapid communications in mass spectrometry 2006, 20, (3), 499-506.

13. wang, n. w.; liu, r. h.; xu, q.; liang, x. m., n-hydroxysuccinimide-promoted oxidation of primary alcohols and aldehydes to form active esters with hypervalent(iii) iodine. chemistry letters 2006, 35, (6), 566-567.

14. ma, x.; xiao, h. b.; liang, x. m., identification of ginsenosides in panax quinquefolium by lc-ms. chromatographia 2006, 64, (1-2), 31-36.
  15. guo, z. m.; lei, a. w.; liang, x. m.; xu, q., click chemistry: a new facile and efficient strategy for preparation of functionalized hplc packings. chemical communications 2006, (43), 4512-4514.

16. zhao, h. x.; zhang, q.; xue, x. y.; liang, x. m.; kettrup, a., predicting gas chromatographic retention times of 209 polybrominated diphenyls (pbbs) for different temperature programs. analytical and bioanalytical chemistry 2005, 382, (5), 1304-1310.

17. zhang, y.; xu, q.; zhang, x. z.; chen, j. p.; liang, x. m.; kettrup, a., high-performance liquid chromatography-tandem mass spectrometry for identification of isoflavones and description of the biotransformation of kudzu root. analytical and bioanalytical chemistry 2005, 383, (5), 787-796.

18. zhang, y.; chen, j. p.; zhang, c. z.; wu, w. z.; liang, x. m., analysis of the estrogenic components in kudzu root by bioassay and high performance liquid chromatography. journal of steroid biochemistry and molecular biology 2005, 94, (4), 375-381.

19. zhang, c. z.; zhang, y. f.; chen, j. p.; liang, x. m., purification and characterization of baicalin-beta-d-glucuronidase hydrolyzing baicalin to baicalein from fresh roots of scutellaria viscidula bge. process biochemistry 2005, 40, (5), 1911-1915.

20. zeng, q. h.; hu, x. p.; duan, z. c.; liang, x. m.; zheng, z., new unsymmetrical hybrid ferrocenylphosphine-phosphoramidite ligands derived from h-8-binol for highly efficient rh-catalyzed enantioselective hydrogenation. tetrahedron-asymmetry 2005, 16, (6), 1233-1238.

21. yu, w. y.; zhang, h.; huang, w. d.; chen, j. p.; liang, x. m., confirmation and identification of the impurities in metolachlor using gas chromatography interfaced with orthogonal acceleration time-of-flight mass spectrometry (gc-oatofms). talanta 2005, 65, (1), 172-178.

22. wang, s. s.; zhao, w. h.; han, x. w.; liang, x. m., two new iridoid glycosides from the tibetan folk medicine swertia franchetiana. chemical & pharmaceutical bulletin 2005, 53, (6), 674-676.

23. wang, n. w.; liu, r. h.; chen, j. p.; liang, x. m., nano2-activated, iron-tempo catalyst system for aerobic alcohol oxidation under mild conditions. chemical communications 2005, (42), 5322-5324.

24. wang, l. x.; zhang, l. f.; wang, s. s.; xiao, h. b.; liang, x. m., discriminating the xanthones in an extract of swertia franchetiana by retention parameters. phytochemical analysis 2005, 16, (1), 34-38.

25. wang, j. c.; guo, r. b.; chen, j. p.; zhang, q.; liang, x. m., phenylurea herbicides-selective polymer prepared by molecular imprinting using n-(4-isopropylphenyl)-n’-butyleneurea as dummy template. analytica chimica acta 2005, 540, (2), 307-315.

26. ma, x. q.; liang, x. m.; xu, q.; zhang, x. z.; xiao, h. b., identification of ginsenosides in roots of panax ginseng by hplc-apci/ms. phytochemical analysis 2005, 16, (3), 181-187.

27. liu, r. h.; dong, c. y.; liang, x. m.; wang, x. j.; hu, x. q., highly efficient catalytic aerobic oxidations of benzylic alcohols in water. journal of organic chemistry 2005, 70, (2), 729-731.

28. liang, x. m.; fu, d. m.; liu, r. h.; zhang, q.; zhang, t. y.; hu, x. q., highly efficient nano2 - catalyzed destruction of trichlorophenol using molecular oxygen. angewandte chemie-international edition 2005, 44, (34), 5520-5523.

29. fu, s. p.; zhang, f.; zhang, x. z.; xu, q.; xiao, h. b.; liang, x. m., physicochemical characterization of the strychnos alkaloids by capillary zone electrophoresis. analytical sciences 2005, 21, (11), 1303-1308.