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| 发布时间：2019-11-28 访问次数:535 作者: |
department of molecular & cellular pharmacology,  school of pharmacy, east china university of science and technology. contact information office:room 629, researching building 18 email: office phone: 86 21 64252044 office fax: 86 21 64252262
education 2001.04 ph.d. applied biosciences , hiroshima prefectural university，hiroshima,japan 1994.07 m.d. shanghai university of traditional chinese medicine,shanghai, p. r. china 1989.07 m.sc. hubai university of traditional chinese medicine, wuhan, p. r. china 1981.07 eng. school of medicine yangzhou university, yangzhou, p. r. china
professional experience 2001.04-professor , school of pharmacy, east china university of science and technology 1996.05-1998.03, sta fellow, institute of physical and chemical research (riken), japan 1995.12-1996.05, sta fellow, osaka bioscience institute（obi）japan 1994.07-1995.12, shanghai university of traditional chinese medicine research interests the basic applied research of the biological antioxidant materials. the filtration of the new anticancer materials and research their function.
publication lei kh, tan sy, du wp, xu yc, lin sc, zheng yh, zou fy, xu yf, liu jw*: 3b, a novel of photosensitizer, exhibited anti-tumor effects via mitochondrial apoptosis pathway in mcf-7 human breast carcinoma cells. tumor biol. 2015,36,5597-5606 zheng yh, zou fy, wang jj, yin gf, le vm, fei zw, and liu jw*:photodynamic therapy-mediated cancer vaccination enhances stem-like phenotype and immune escape, which can be blocked by thrombospondin-1 signaling through cd47 receptor protein. j biol chem. 2015, 290, 8975-8986 lin sc, lei kc, du wp, yang ly, shi hy, gao yw, yin ph, liang x, liu jw*: enhancement of oxaliplatin sensitivity in human colorectal cancer by hypericin mediated photodynamic therapy via ros-related mechanism. int j biochem cell b 2016, 71,24-34 zheng yh, yin gf, le vm, zhang al, yin ph, liu jw*, photodynamic-therapy activates immune response by disrupting immunity homeostasis of tumor cells, which generates vaccine for cancer therapy int j biol sci 2016, 12(1),120-132. zou fy, mao rr, lei kc, yang ly, ding y, zhang p, li jy, liang xin, liu jw*: targeted deletion of mir-139-5p enhances colon inflammation and tumorigenesis through negatively regulating mapk, nf-κb, and stat3 signaling pathways. febs journal, 2016,283,1438-1452. xin liang, haiyang shi, liyan yang, cen qiu, shengchao lin, yingxue qi, jiyu li, aiguang zhao, and jianwen liu*: inhibition of polypyrimidine tract-binding protein 3 induces apoptosis and cell cycle arrest, and enhances the cytotoxicity of 5- fluorouracil in gastric cancer cells. br j cancer. 2017, 116(7):903-911. xin liang*, weixia chen, haiyang shi, xiangyu gu, yueqi li, yingxue qi, ke xu*, aiguang zhao*, jianwen liu*. ptbp3 contributes to the metastasis of gastric cancer by mediating cav1 alternative splicing. cell death & disease. 2018, 11:117 yueqi li, yiyang chen, cen qiu, xiaoying ma, kecheng lei, guoxiang cai, xin liang, jianwen liu*: 17-allylamino-17-demethoxygeldanamycinimpeded chemotherapy through antioxidant activation via reducing ros-induced cell death. j cell biochem. 2018; 1-17. yingxue qi, wenchun chen, xinyu liang, ke xu*, xiangyu gu, fengying wu, xuemei fan, shengxiang ren, junling liu, jun zhang6, renhao li, jianwen liu*, xin liang*: novel antibodies against gpibα inhibit pulmonary metastasis by affecting vwf-gpibα interaction journal of hematology & oncology. 2018, 11(1):117. 1, xiaoying ma, jiajun liu, jiyu li, yueqi li, van minh le, shaoyu li, xin liang, lingshuang liu, jianwen liu*: mir‐139‐5p reverses stemness maintenance and metastasis of colon cancer stem‐like cells by targeting e2‐2 j cell physiol. 2019;1-16. yuyu zhao, jiajun xu, van minh le, qianyi gong, shaoyu li, feng gao, lei ni*, jianwen liu*, xin liang*: epcam aptamer-functionalized cationic liposome-based nanoparticles loaded with mir-139-5p for targeted therapy in colorectal cancer. mol. pharmaceutics 2019, 16, 4696-4710
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